Intercellular interaction dictates cancer cell ferroptosis via NF2 …
https://pubmed.ncbi.nlm.nih.gov/31341276/
Ferroptosis, a cell death process driven by cellular metabolism and iron-dependent lipid peroxidation, has been implicated in diseases such as ischaemic organ damage and cancer 1,2.The enzyme glutathione peroxidase 4 (GPX4) is a central regulator of ferroptosis, and protects cells by neutralizing lipid peroxides, which are by-products of cellular metabolism.
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