pde4 inhibitor | Phosphodiesterase Inhibitors - StatPearls

Keyword	CPC	PCC	Volume	Score	Length of keyword
pde4 inhibitor	0.07	0.5	5500	58	14
pde4	1.53	0.2	5105	97	4
inhibitor	1.48	0.2	8864	62	9

Keyword	CPC	PCC	Volume	Score
pde4 inhibitors	1.42	0.6	1146	16
pde4 inhibitor drugs	1.97	1	3194	74
pde4 inhibitor copd	0.99	0.4	2023	38
pde4 inhibitor atopic dermatitis	0.33	0.8	1448	78
pde4 inhibitor copd examples	1.95	0.6	6423	81
pde4 inhibitor mechanism of action	1.69	0.7	9931	38
pde4 inhibitor moa	0.37	0.8	6096	86
pde4 inhibitor cream	0.7	0.8	6458	46
pde4 inhibitor eczema	0.24	0.6	5503	81
pde4 inhibitor ibd	0.66	0.7	1781	10
pde4 inhibitor psoriasis	1.3	0.9	8273	17
pde4 inhibitor roflumilast	1.66	0.7	4425	6
phosphodiesterase 4 pde4 inhibitor	1.18	0.3	4273	60
what is pde4 inhibitors	0.79	0.3	9501	31
topical pde4 inhibitor psoriasis	1.04	0.5	1332	16
phosphodiesterase-4 pde4 inhibitors	0.65	1	5836	35
what is a pde4 inhibitor	0.77	0.1	1014	20
pde4 inhibitors drugs	0.17	0.2	7568	65
pde4 inhibitors copd	1.56	0.3	5110	26
pde4 inhibitors examples	0.66	0.2	394	78
pde4 inhibitors for psoriasis	0.75	0.8	2954	60
pde4 inhibitors list	1.49	0.1	3569	69
pde4 inhibitors mechanism of action	1.1	0.2	5326	93
pde4 inhibitors drug list	1.63	0.3	2697	57
pde4 inhibitors side effects	0.04	0.5	6746	53
pde4 inhibitors for atopic dermatitis	0.07	0.7	843	32
how does pde4 inhibitor work in lungs	0.23	0.2	6192	15
natural pde4 inhibitors	0.01	0.2	4138	64
oral pde4 inhibitors	0.82	0.8	2353	73
list of pde4 inhibitor drugs	0.51	0.8	5321	45

Search Results related to pde4 inhibitor on Search Engine

Phosphodiesterase Inhibitors - StatPearls - NCBI Bookshelf
nih.gov

https://www.ncbi.nlm.nih.gov/books/NBK559276/

WEBJun 26, 2023 · PDE-4 is an enzyme found in cells of the lungs, and PDE-4 inhibitors inhibit the degradation of intracellular cyclic adenosine monophosphate(cAMP) and increase cAMP levels in target cells, further causing bronchial muscle relaxation. Along with its effects on the lungs, it also decreases pro-inflammatory mediators. These agents are …

DA: 69 PA: 73 MOZ Rank: 59

Phosphodiesterase-4 inhibitor - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Phosphodiesterase-4_inhibitor

WEBRolipram, the prototypical PDE4 inhibitor. A phosphodiesterase-4 inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic adenosine monophosphate (cAMP). It is a member of the larger family of PDE inhibitors.

DA: 21 PA: 64 MOZ Rank: 80

Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199465/

WEBOct 17, 2018 · PDE4 inhibitors developed for the treatment of neuroinflammation. Accumulating evidence indicated that neuroinflammation largely initiates and exacerbates the process of nervous system diseases, including depression, Alzheimer's disease, multiple sclerosis, etc. (Heneka et al., 2015).

DA: 20 PA: 73 MOZ Rank: 91

An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370432/

WEBAug 4, 2022 · PDE4-targeted therapy has also shown promising results in other neurological disorders and the same Rolipram, the first blood-brain-barrier permeable PDE4 inhibitor, has been proven to be effective in various animal models of Parkinson’s disease, Alzheimer’s disease, depression and neuropathic pain [159,160,161].

DA: 41 PA: 28 MOZ Rank: 11

PDE4 inhibitors for disease therapy: advances and future …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/37470147/

WEBJul 20, 2023 · This review provides a comprehensive summary of the development of PDE4 inhibitors in the past few years, along with the structure, clinical and research progress of multiple inhibitors of PDE4, focusing on the research and …

DA: 58 PA: 69 MOZ Rank: 54

The Molecular Biology of Phosphodiesterase 4 Enzymes as ... - PubMed
nih.gov

https://pubmed.ncbi.nlm.nih.gov/34233947/

WEBPhosphodiesterase 4 Inhibitors. Protein Isoforms. Cyclic Nucleotide Phosphodiesterases, Type 4. The phosphodiesterase 4 (PDE4) enzyme family plays a pivotal role in regulating levels of the second messenger cAMP.

DA: 46 PA: 27 MOZ Rank: 96

Phosphodiesterase Inhibitors: Types and Purpose - Cleveland Clinic
clevelandclinic.org

https://my.clevelandclinic.org/health/treatments/23211-phosphodiesterase-inhibitors

WEBPDE-4: This type is specific to your lungs, causing muscles in your airway (especially your bronchial tubes) to constrict and tense up. PDE-5: These are in the lungs, and in the penis (for those assigned male sex at birth). Phosphodiesterase (PDE) inhibitors are medications that block those enzymes.

DA: 28 PA: 60 MOZ Rank: 82

PDE4 Inhibitors for Psoriasis: What to Know - Healthline
healthline.com

https://www.healthline.com/health/psoriasis/pde4-inhibitors-need-to-know

WEBApr 20, 2020 · PDE4 inhibitors, like apremilast (Otezla), work inside the body to prevent inflammation. As a preventive measure, it may be beneficial for people with psoriasis to manage inflammation. Reducing...

DA: 10 PA: 17 MOZ Rank: 69

PDE4 inhibitors for disease therapy: advances and future …
future-science.com

https://www.future-science.com/doi/10.4155/fmc-2023-0101

WEBJul 20, 2023 · PDE4 inhibitors for disease therapy: advances and future perspective | Future Medicinal Chemistry. Future Medicinal Chemistry Vol. 15, No. 13. Review. PDE4 inhibitors for disease therapy: advances and future perspective. Baochan Du‡. , Min Luo‡. , Changyu Ren. & Jifa Zhang. Published Online: 20 Jul 2023 https://doi.org/10.4155/fmc …

DA: 77 PA: 41 MOZ Rank: 92

An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022
nih.gov

https://pubmed.ncbi.nlm.nih.gov/35956914/

WEBAug 4, 2022 · Phosphodiesterase 4 Inhibitors. Cyclic Nucleotide Phosphodiesterases, Type 4. Grants and funding. This research received no external funding. Since the early 1980s, phosphodiesterase 4 (PDE4) has been an attractive target for the treatment of inflammation-based diseases.

DA: 20 PA: 65 MOZ Rank: 12