Apixaban Drug Interaction Potential. The absorption of apixaban is mediated by P-glycoprotein (P-gp). P-gp inhibitors can increase the absorption of apixaban, increasing both AUC and Cmax. Conversely, P-gp inducers can reduce the absorption of apixaban, decreasing AUC and Cmax. 2. The metabolism of apixaban is mediated by CYP3A4.Can you drink alcohol while taking apixaban?
May need to avoid alcohol, cranberry juice, and products containing cranberries. Click to see full answer. Subsequently, one may also ask, can you take apixaban with food? Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take apixaban with or without food.Can herbal supplements interfere with apixaban (Eliquis)?
Answer: Yes, several popular herbal supplements can impact the effectiveness of apixaban (Eliquis), rivaroxaban (Xarelto), betrixaban (Bevyxxa), and other anticoagulant drugs (blood-thinners) classified as direct factor Xa inhibitors. These blood-thinners are broken down in the body by the liver enzyme CYP3A4.What foods should you not eat with apixaban?
Avoid foods high in Vitamin K, e.g. large amounts of leafy green vegetables and some vegetable oils. May need to avoid alcohol, cranberry juice, and products containing cranberries. Click to see full answer. Subsequently, one may also ask, can you take apixaban with food?