Keyword Analysis & Research: apixaban by mouth

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What is the generic name for apixaban?

Generic name: apixaban (a PIX a ban) Brand name: Eliquis, Eliquis Starter Pack for Treatment of DVT and PE. Dosage forms: oral tablet (2.5 mg; 5 mg) Drug class: Factor Xa inhibitors. Medically reviewed by on June 11, 2021. Written by Cerner Multum. Uses. Warnings. Dosage.

How do you take apixaban without food?

You may take apixaban with or without food. If you cannot swallow a tablet whole, crush and mix it with water, apple juice, or a spoonful of applesauce. Swallow the mixture right away without chewing. Do not save it for later use. A crushed tablet mixture may also be given through a nasogastric (NG) feeding tube.

Is apixaban (Eliquis) a good anticoagulant?

Apixaban (Eliquis) was recently approved as an oral anticoagulant (a direct inhibitor of factor Xa) to reduce the risk of embolism in patients with atrial fibrillation.

What is the mechanism of action of apixaban?

Mechanism of action. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. Apixaban has no direct effect on platelet aggregation, but by inhibiting factor Xa, it indirectly decreases clot formation induced by thrombin.

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