Keyword Analysis & Research: apixaban package insert

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Frequently Asked Questions

What drugs should not be taken with apixaban?

Combined P-gp and Strong CYP3A4 Inhibitors: Inhibitors of P-glycoprotein (P-gp) and cytochrome P450 3A4 (CYP3A4) increase exposure to apixaban and increase the risk of bleeding.

Does apixaban (Eliquis) have anti-FXa activity?

ELIQUIS (apixaban) Product Monograph Page 9 of 79 Apixaban demonstrates anti-FXa activity as evident by reduction in Factor-Xa enzyme activity in the Rotachrom® Heparin Anti-Xa assay data from clinical studies.

How much Apixaban can you take in a day?

In controlled clinical trials, orally administered apixaban in healthy subjects at doses up to 50 mg daily for 3 to 7 days (25 mg twice-daily for 7 days or 50 mg once-daily for 3 days) had no clinically relevant adverse effects.

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