Buspar generally takes about 1 to 2 weeks of consistent dosing to notice clinical effects. For this reason, it is not for the immediate relief of anxiety symptoms. It can take up to 4 to 6 weeks of dosing for maximum effects.How does Buspar affect dopamine?
Buspirone (BuSpar) binds to receptors for serotonin and dopamine. The effect is to increase serotonin activity and decrease dopamine activity in the brain. Like the selective serotonin reuptake inhibitors (SSRIs), buspirone is used for the long-term treatment of generalized anxiety disorder.