Keyword Analysis & Research: catalogue of somatic mutations

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Frequently Asked Questions

Which is the catalogue of somatic mutations in cancer?

COSMIC, the Catalogue Of Somatic Mutations In Cancer, draws together the available information about the effects of somatic mutations across the range of human cancers.

How many mutations are there in COSMIC cancer?

The latest release, COSMIC v86 (August 2018), includes almost 6 million coding mutations across 1.4 million tumour samples, curated from over 26 000 publications.

How are non coding mutations related to cancer?

In addition to coding mutations, COSMIC covers all the genetic mechanisms by which somatic mutations promote cancer, including non-coding mutations, gene fusions, copy-number variants and drug-resistance mutations. COSMIC is primarily hand-curated, ensuring quality, accuracy and descriptive data capture.

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