We therefore endorse the AHA cautionary approach of recommending 2 weeks of aminoglycosides in addition to 4 weeks penicillin for even sensitive strains. As information on endocarditis caused by group C and G streptococci is so limited, 4 weeks penicillin with 2 weeks gentamicin is also recommended.When to switch from intravenous to oral antibiotics for endocarditis?
Patients with infective endocarditis on the left side of the heart are typically treated with intravenous antibiotic agents for up to 6 weeks. Whether a shift from intravenous to oral antibiotics once the patient is in stable condition would result in efficacy and safety similar to those with continued intravenous treatment is unknown.How long does infective endocarditis take to heal?
Drs. Iversen, Ihlemann, Høfsten, Fosbøll, Køber, and Bundgaard are members of Copenhagen Health Science Partners. Patients with infective endocarditis on the left side of the heart are typically treated with intravenous antibiotic agents for up to 6 weeks.Which is the best antibiotic for native valve endocarditis?
For native valve endocarditis, there is evidence that 4 weeks of high-dose penicillin can be used for sensitive streptococci (MIC ≤ 0.1 mg/L), and that short-course treatment (2 weeks penicillin in combination with gentamicin) may be as effective.