Keyword Analysis & Research: fischer esterification

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What do you need to know about Fischer esterification?

Fischer Esterification. Fischer esterification is the esterification of a Carboxylic acid by heating it with an alcohol in the presence of a strong acid as the catalyst.

Which is a limitation of Fischer esterification of tertiary alcohol?

Another limitation of Fischer esterification is the fact that tertiary alcohols undergo a “fast” dehydration in presence of strong acids: In these situations, alternative strategies such as the higher reactivity of acid chlorides and the carboxylate salts, discussed above, can be used to prepare the desired ester.

When does acetic acid react with Fischer esterification?

If conditions are acidic enough, the acetic acid can be further reacted via the Fischer esterification pathway, but at a much slower pace.

How is esterification done in an undergraduate lab?

Typically students start with a known acid and known alcohol and produce a pleasant-smelling ester, that is considered to be the unknown [5-8] In this undergraduate lab, students carry out a Fisher esterification synthesis with cinnamic acid and one of multiple simple alcohols, such as ethanol, propanol, butanol, iso -butanol, hexanol.


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