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There are 102.18 miles from Florida City to Key West in southwest direction and 126 miles (202.78 kilometers) by car, following the US-1 route. Florida City and Key West are 2 hours 38 mins far apart, if you drive non-stop.How far is it from Tampa to Florida Keys?
Distance from Tampa to Key West. Distance between Tampa and Key West is 383 kilometers (238 miles). Driving distance from Tampa to Key West is 685 kilometers (426 miles).