Gastrointestinal stromal tumors (GISTs) are tumors, or clusters of overgrown cells, in the gastrointestinal (GI) tract. Symptoms of GIST tumors include: bloody stools. pain or discomfort in the abdomen. nausea and vomiting. bowel obstruction.What causes Gist cancer?
Cancers can be caused by DNA changes that turn on oncogenes or turn off tumor suppressor genes. The gene changes that lead to most GISTs are now understood, but it’s still not clear why these changes occur. There are no known lifestyle-related or environmental causes of GIST.What are the symptoms of GIST cancer?
Symptoms of GIST tumors include: bloody stools. pain or discomfort in the abdomen. nausea and vomiting. bowel obstruction. a mass in the abdomen that you can feel. fatigue or feeling very tired.Are GIST tumors always malignant?
Small tumors are generally benign, especially when cell division rate is slow, but large tumors disseminate to the liver, omentum and peritoneal cavity. 2. All GIST tumors are now considered to have malignant potential, and no GIST tumor can be definitively classified as "benign".