Keyword Analysis & Research: langerhanszellen

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What is the shape of a Langerhans cell?

Langerhans cell is represented by a yellow oval; blue arrows correspond to is_a relations, and orange arrows correspond to develops_from relations. Only a subset of Langerhans cell parent types are included in the figure. Langerhans cells (LC) are tissue-resident dendritic cells of the skin, and contain organelles called Birbeck granules.

What is multifocal Langerhans cell (LCH) disease?

Multifocal multisystem LCH, also called Letterer-Siwe disease, is a rapidly progressing disease in which Langerhans Cell cells proliferate in many tissues.

What is the function of Langerhans cells in skin infections?

Function. In skin infections, the local Langerhans cells take up and process microbial antigens to become fully functional antigen-presenting cells . Generally, dendritic cells in tissue are active in the capture, uptake and processing of antigens. Once dendritic cells arrive in secondary lymphoid tissue, however,...

Is Langerhans cell histiocytosis a myeloproliferative disorder?

This study documented the first recurrent mutation in LCH samples. Two independent studies have confirmed this finding. Presence of this activating mutation could support the notion to characterize LCH as myeloproliferative disorder. Micrograph showing Langerhans Cell Histiocytosis.


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