Causes. The most common causes of splenomegaly in developed countries are infectious mononucleosis, splenic infiltration with cancer cells from a hematological malignancy and portal hypertension (most commonly secondary to liver disease, and sarcoidosis). Splenomegaly may also come from bacterial infections,...What is splenomegaly disease?
Splenomegaly is a medical condition in which the spleen becomes enlarged. Causes for splenomegaly may include infections, blood cancers, liver diseases, and metabolic disorders, or even undue pressure on the liver and spleen's veins or blood clots in those veins. Specific diseases that may cause the condition include...What is mild splenomegaly?
Splenomegaly is defined as enlargement of the spleen, measured by size or weight.In the past, splenomegaly was a clinical finding, but in recent years, imaging studies have also helped to assess for or confirm mild splenomegaly. The spleen is a functionally diverse organ with active roles in immunosurveillance and hematopoiesis.