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What causes an enlarged spleen or splenomegaly?

Overview. Your spleen is an organ located just below your left rib cage. Many conditions — including infections, liver disease and some cancers — can cause an enlarged spleen, also known as splenomegaly (spleh-no-MEG-uh-lee).

What does hepatic and splenic tuberculosis mean?

Hepatic and splenic tuberculosis. Hepatic and splenic tuberculosis refers to tuberculosis affecting the liver and the spleen. It generally occurs due to haematogenous spread from the primary site of infection, commonly from pulmonary tuberculosis.

When to seek medical attention for splenomegaly?

Splenomegaly is a serious condition and it is recommended to seek out immediate medical attention if spleen enlargement is suspected. An enlarged spleen can rupture easily upon trauma and, in some cases, can rupture spontaneously. Splenic rupture can lead to a life-threatening loss of blood.

What are the liver test results for splenomegaly?

Liver test results are diffusely abnormal in congestive splenomegaly with cirrhosis; an isolated elevation of serum alkaline phosphatase suggests hepatic infiltration, as in myeloproliferative and lymphoproliferative disorders, miliary tuberculosis , and chronic fungal diseases (eg, candidiasis , histoplasmosis ).


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