PKC designs, manufactures and integrates electrical distribution systems, electronics and related architectural components for the commercial vehicle industry, rolling stock manufacturers and selected other segments. Read more
PKC Group is a trusted and acknowledged partner in global commercial vehicle industry. PKC designs, manufactures and integrates electrical distribution systems, electronics and related architectural components for the commercial vehicle industry, rolling stock manufacturers and selected other segments.How is protein kinase C ( PKC ) related to PARP?
Protein kinase C (PKC) pathway and poly (ADP-ribose) polymerase (PARP) Protein kinase C (PKC) is involved in controlling the function of proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins.How is phosphorylation of other proteins performed by PKC?
These functions are achieved by PKC-mediated phosphorylation of other proteins. However, the substrate proteins present for phosphorylation vary, since protein expression is different between different kinds of cells. Thus, effects of PKC are cell-type-specific: increase salivary potassium levels.How is PKC activation related to endothelial permeability?
Low-level PKC activation is sufficient to reverse cell chirality through phosphatidylinositol 3-kinase/AKT signaling and alters junctional protein organization between cells with opposite chirality, leading to an unexpected substantial change in endothelial permeability, which often leads to inflammation and disease.
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